Pycnogenol is known under different names in some countries, such as Oligopin, and Flavangenol in Japan [4, 5]. Although the preliminary studies show many health benefits with the use of Pycnogenol, future larger and better studies are needed. Sort By. Pycnogenol (125 mg/day) had the same effects in another study of 48 people with diabetes and high blood pressure. Pycnogenol: French maritime pine bark extract How to Get Rid of Hemorrhoids (4+ Natural Remedies) - Dr. Axe What gives pine bark extract its notoriety as a powerful ingredient and super antioxidant is that its loaded with oligomeric proanthocyanidin compounds, OPCs for short. Comment * document.getElementById("comment").setAttribute( "id", "a79cdfe7a30d8f84d45d97f833c00b8c" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. Pycnogenol, an extract of French maritime pine bark, helps the body fight normal aging by supporting vascular health and healthy circulation. PQQ Supplements: Overview, Benefits, and Side Effects - Healthline Pycnogenol may stimulate the immune system. Researchers suggest that it may epigenetically turn off genes responsible for joint damage (ADAMTS) as well as reduce inflammation enzymes (MMP3) and cytokines (IL 1-beta) [47, 48]. Pycnogenol is the leading ingredient in Isotonix OPC-3, Market America's best-. ", Panminerva Medica: "Supplementation with Pycnogenol improves signs and symptoms of menopausal transition.". Subjects in the study that took Pycnogenol ended up taking fewer painkillers [51]. Commonly called arthritis, osteoarthritis is caused when the cartilage on your joints begins to wear down. Today, I want to share with you my secrets to reduce sugar Top 7 Benefits of Green Tea: The No. A study of 68 people found that Pycnogenol, started 2 days prior to flying, may reduce the duration of jet lag symptoms [83]. Vinpocetine is a well-known substance in the health-hacking community with a variety of claimed health benefits. In a clinical trial of 92 people with tinnitus, or ringing in the ears, Pycnogenol (100-150 mg/day) helped reduce symptoms and improve blood flow in the ears after 4 weeks [80]. The dosage in most clinical studies varied between 50-360 mg/day. Lutein uses and benefits include helping prevent eye conditions like macular degeneration and cataracts, skin disorders and skin cancer, several types of cancer, including colon or breast cancer, type 2 diabetes, and heart disease. Set Ascending Direction. Regardless of what youre using it for, its best to start with the lowest possible dose. This condition can be temporary or permanent however, some studies have indicated that pine bark extract may help alleviate these symptoms due to its high presence of antioxidants. Lower the risk of Alzheimer's disease. You can find out your systolic blood pressure by looking at the top number of a blood pressure test. 5 6 However, evidence is conflictingother studies have shown no effect on the same measures. There is a seemingly growing problem with skin exposure to ultraviolet radiation and the confusion of how to get vitamin D from the sun while avoiding these skin-damaging rays. It also may help regenerate and maintain vitamin C and E levels while also potentially increasing nitric oxide levels, which may relax and protect blood vessels [1]. Pycnogenol Benefits, Dosage & Side Effects - Ayur Times We do not aim to diagnose, treat, cure or prevent any illness or disease. Risks. Inhibits platelet aggregation like low-dose aspirin. The outcome showed significant healing when compared to those subjects who were not given any drug or remedy, concluding that Pycnogenol may be an effective remedy for healing of surgery-related lesions. Diindolylmethane, or DIM for short, is a plant indolea plant compound with health-promoting properties. It may cause side effects such as: Dizziness. Most have similar amounts of active substances and are often sold under the brand name Pycnogenol [6]. ", Natural Medicines Comprehensive Database web site: "Pycnogenol.". We avoid using tertiary references. A randomized clinical trial of 30 people found that Pycnogenol (150 mg/day) may help heal vein ulcers from surgery and reduce swelling after 3 months of treatment [25]. Not bad. If you take any medications regularly, talk to your doctor before you start using pycnogenol supplements. Learn more. A 10 week clinical trial with 30 children shows that Pycnogenol may improve symptoms of Crohns disease. (2012). Pycnogenol seems well-tolerated for use in adults for up to 6 months. In some people lung inflammation is caused by leukotrienes chemicals that are released by the body after a person encounters allergens. Learn more about how to get even skin tone. A randomized, double-blind, placebo-controlled study of 60 patients aged six to 18 years old, was conducted over three months during which patients were randomly assigned to receive either Pycnogenol or placebo. Therefore, those who have autoimmune conditions could see their symptoms increase after taking it., Since Pycnogenol is used for so many conditions, doses can vary. However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. All rights reserved. All of our content is written by scientists and people with a strong science background. Whole Foods Organic Allergy Medicine-drug DIM and other plant indoles are found in . First and foremost, start eating an anti-inflammatory Local Raw Honey (Bee Pollen) Considering how good it tastes, having some raw honey Apple Cider Vinegar (ACV) You can now find high-quality apple cider vinegar in . Masquelier was easily able to create a pine bark extract from materials that were otherwise known as waste. Symptoms include swelling in ankles and legs, discolored skin and, if the skin is broken, the development of leg ulcers. However, it can also be used topically. In a small/preliminary study of kids with asthma, pycnogenol helped improve symptoms. (2006). Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein. Pycnogenol is a compound of natural chemicals. Pycnogenol was featured on The Dr. Oz Show in January 2013, . According to a study of 11 patients with lupus, pycnogenol may reduce symptoms, inflammation, and oxidative stress [54]. painful urination. However, these studies appear to be methodologically sound and reliable, with no blatant errors in the study design and data collection. Pycnogenol (100 mg/day) improved menopausal symptoms and quality of life in a clinical trial of 35 women after 8 weeks [68]. If you feel that any of our content is inaccurate, out-of-date, or otherwise questionable, please leave a comment or contact us at [emailprotected]. In 7 volunteers, Pycnogenol (300 mg) for 5 days may reduce the activity of a crucial inflammatory gene (NF-B) [53]. Dr. Steven Lamm did a great job at explaining the new benefits of pycnogenol. A small 2017 study examined the effects of pine bark extract in treating cardiovascular risk factors associated with menopause. A study was conducted by the Guang An Men Hospital of Chinese Medical Science Research Institutewith 77 diabetes type II patients to determine if theextract of the French Maritime pine bark provided anti-diabetic effects. Another study found this supplement can even halt progression of vision . Pycnogenol lotions applied postirradiation reduced this immunosuppression to 22% (0.05% Pycnogenol) and 13% (0.1% Pycnogenol). There is currently insufficient evidence to determine what a safe and effective dose of lysine is for specific conditions. (2017). A total of 40 patients with retinopathy (damage to the retina part of the eye) from diabetes and other vascular causes were enrolled in one study. Pycnogenol Review - Worlds Best Anti-Aging Supplement? , Improves Symptoms Associated With Menopause, A number of women experience physical discomfort due to symptoms of menopause. Grapes: Health Benefits, Nutrition, Recipes and Risks - Dr. Axe 7 Health Benefits of Pine Bark Extract - Natures Fare Jonathan Ritter, PharmD, PhD (Pharmacology), Small molecule antioxidants (phenolic acids, catechin, and taxifolin) are quickly absorbed and begin to act in the body within 30 min, The remaining more complex antioxidants (long chains of procyanidins) reach the gut, where your, The microbiome-produced active compounds appear in blood 6 h later and remain for at least 14 h, Pycnogenol is standardized to contain 70 5% procyanidins, which should be on the label, Pycnogenol standardization doesnt determine other major active compounds, which can vary. Herbal supplements are not regulated by the Food and Drug Administration (FDA), so they may not be up to the same safety standards as medications that have gone through clinical testing and drug trials. 8 Proven Benefits of Pine Bark Extract - Healthy Focus In patients with chronic venous insufficiency, the number of muscle cramps decreased from 6.3 to 2.6; in athletes from 8.6 to 2.4. The specific tree from which the bark is extracted is called a maritime pine. Mental function. A review was conducted of French maritimepine bark extract, specifically using the nutritional supplement Pycnogenol. Its been noted that taking OPCs and vitamin C supplements at the same time could increase blood pressure if you have hypertension. The same study showed that a single, 200-mg Pycnogenol dose remained effective over six days in preventing cigarette-induced enhanced platelet aggregation. The 2012 study on the anti-aging benefits of Pycnogenol is commonly-cited by anti-aging supplement manufacturers. Researchers from the study suggest that low Pycnogenol dosage and short study duration may explain the lack of benefits [44]. Chanca Piedra: Benefits, Dosage, Side Effects, and More - Healthline Some people who have asthma have higher levels of leukotrienes in their blood. Studies have also safely used Pycnogenol in children and during pregnancy. In a third study, 19 men with fertility problems were given 200 mg Pycnogenol daily for 90 days. 6 Amazing Benefits of Nattokinase | Organic Facts (11, 12), While both eliminate pain, the pine bark extract is a far better choice. 11 Skin elasticity increased, and skin fatigue decreased significantly in this study as well, further lowering the wrinkling risk. In those treated with Pycnogenol, the edema score was increased by 17.9% versus an increase of 58.3% in the control group. (2004). Healthline Media does not provide medical advice, diagnosis, or treatment. Studies on human subjects have reported few side effects - even . Andrographis is a medicinal herb used to treat many health conditions, such as the common cold, osteoarthritis, and ulcerative colitis. There were 88 in the control group and 81 in the Pycnogenol group. 2005-2023 Healthline Media a Red Ventures Company. A 2011 study by Dr. G. Belcaro concluded, " Pycnogenol administration was effective for better control of signs and symptoms of allergic asthma and reduced the need for medication". Pycnogenol supplementation reduced skin redness from UV rays in a trial of 21 people over 8 weeks. A study with four groups of 30 patients each were studied: (1) systemic Pycnogenol and local application; (2) local Pycnogenol only; (3) oral Pycnogenol and (4) medications only (control). Luckily, the Native Americans told them about a tea prepared from the bark of a certain tree, which miraculously led to complete recovery. Low-dose Pycnogenol (30 mg/day) may reduce pain in pregnant women, particularly hip, joint, lower back, groin, and calf cramps in the third trimester [71]. The combination of Panax ginseng and vitamin E also appears to have an effect. Pycnogenol may reduce glucose levels, but it doesnt appear to increase insulin production or insulin sensitivity. We all know the power of antioxidants to improve health and thehigh-antioxidant foodswe should eat regularly. A 2004 animal study also found that applying a gel containing pine bark extract sped up the wound-healing process. Remember to speak with a doctor before taking Pycnogenol. Pycnogenol has been shown to help relieve the pain associated with osteoarthritis by keeping blood chemicals from attacking the cartilage. Amazon.com: Healthy Origins Pycnogenol 100 mg (Nature's Super Potential for allergy when taken orally or used on the skin. Pycnogenol is a patented formulation of Pine Bark Extract which is standardized to 65-75% Procyanidin compounds by weight. According to some researchers, Pycnogenol may lower blood pressure by relaxing blood vessels, reducing free radicals, and lowering inflammation. For children with ADHD, research suggests that symptoms start to return after about a month without taking maritime pine, so taking periodic breaks shouldnt make it any less effective. There havent been any studies looking at long-term liver damage. Proper nutrition is essential for ADHD treatment. Moreover, Pycnogenol treatment led to an increase in sperm count and testosterone levels with lowering of blood pressure and cholesterol levels. Ginkgo biloba has been widely cultivated across the globe for a variety of uses, most of which are medicinal. You may want to start slow, taking smaller amounts, to ensure that your body works well with the OPCs found in pine bark extract. Sign Up for the Latest Health News and Tips, Home Food and Nutrition Pycnogenol (French Maritime Pine Bark Extract): 12 Benefits According to Studies. The study provided clear evidence that Pycnogenol does, indeed, offer photoprotection however, it came out even better than expected, showing that it may be used to reduce hyperpigmentation of human skin while improving the skin barrier function and extracellular matrix homeostasis. (6). Also, be sure to talk with your doctor first if you have an underlying medical condition or take other medications. A popular variety is the pinus maritime or the maritime pine that grows exclusively along the coast of southwest France. In mice, luteolin prevented inflammation and allergic response in the lungs and nose by inhibiting inflammatory cytokines: IL-4, IL-5, and IL-1 3 []. DOI: Chowdhury WK, et al. The extract has been widely studied for the past 40 . 1) Encourages Healthy Blood Pressure. Finally, research suggests that Pycnogenol may improve triathlon time while possibly reducing cramps and post-running pain [10]. It should never be used as a replacement for approved medical therapies. If you choose to use Pycnogenol, follow the dosage instructions on the label. While pine bark extract is thought to be safe for children, they should only take it for a few weeks at a time. Moreover, Pycnogenol treatment reduced the use of painkillers. If possible, try to get pine bark extract from a local supplier, such as a health food store. 40 years of research has been dedicated to establishing the safety of Pycnogenol and its benefits for human health. In 1535, a French explorer by the name of Jacques Cartier found himself ice-bound on the St. Lawrence River. 8 Proven Benefits of L-arginine - Nutrition and Fitness Central However, in all the above studies insulin levels did not change. Additionally, athletes have endured less cramping and muscle pain when using the extract. Some people seek to manage ADHD symptoms through an ADHD diet. 10 Day Erection Delay Sex Pills. $31.99. Upset stomach. Also, its important to note that some of these studies were funded by Horphag Research, the original developers and exclusive marketers of Pycnogenol. A sitz bath, which involves sitting in warm water for 10 minutes, twice daily, is helpful to patients with anal itching, aching or burning and is known as one of the best ways to get rid of hemorrhoids fast. Improve cardiovascular health. Benefits, Nutrition, Uses & How It Compares vs. Blackberries. Disease of the retina in the eye. New studies show Pycnogenol can prevent or reverse the oxidative damage that produces blood vessel disease 4, metabolic syndrome 20, diabetes 20,24, and neurodegenerative disorders 23,24. More research is needed to see how this supplement affects all of these conditions. Animal studies have found that gotu kola makes it harder . Research suggests that taking pycnogenol improves mental function and memory in both young adults and the elderly. Pycnogenol - Herbal Supplements - Healthy Planet In another trial, 30 people with type 2 diabetes received a range of pycnogenol doses. In a study of 77 people with symptoms of Irritable Bowel Syndrome (IBS), Pycnogenol (150 mg/day) improved symptoms and reduced the frequency of attacks [77]. Possible side effects . It also may help those on blood pressure medications to reduce their dose [32]. Chronic Obstructive Pulmonary Disease (COPD) is a chronic lung disease caused primarily by tobacco use. Pycnogenol: Skin, ADHD, Other Uses, Side Effects - Healthline DOI: Dvorkov M, et al. Studies have found that nattokinase thins the blood and dissolves accumulated solids in it. This nerve affects our balance and hearing by sending signals to the brain. Top 10 Health Benefits of Nattokinase - Earth Clinic Pycnogenol Benefits - Dr Sarah Brewer Circulation and Jet Lag on Long Flights. It also may enhance swimming, biking, and running scores in professional athletes preparing for a triathlon (at 150 mg/day). Certain studies used combination products, so its unknown what the contribution of Pycnogenol itself was. Furthermore, when CHS was suppressed by 71% with exogenous treatment with cis-urocanic acid, the putative epidermal mediator of photoimmunosuppression, 0.2% Pycnogenol lotion reduced the immunosuppression to 18%. Read More: Health Benefits of Peanut Butter. whole-body health. The combination of L-arginine and Pycnogenol may help in erectile dysfunction by boosting nitric oxide, which potentially could improve blood flow in men [66]. (2017). It decreased concussion symptoms in 42 student-athletes with a history of sports-related concussions after 6 weeks. These antioxidants scavenge those damaging free radicals in an effort to eliminate them, ultimately preventing disease. Ana spent years working with patients who suffer from various mental health issues and chronic health problems. Quality and active ingredients in supplements may vary widely from maker to maker. One study involved a four-week treatment period followed by one week of no treatment or observation period. Pine bark extract comes from the inner bark of the Pinus pinaster tree, most commonly found in Europe. Blood clots form as a result of platelet aggregation, which is the platelets in the blood clumping together. A systematic review of 14 studies found that Pycnogenol gum or mouthwashes may reduce dental plaque, but the quality of evidence is low [58, 59]. SelfDecode does not treat, diagnose or cure any conditions, Pine bark extract can be found in liquid, tablet or capsule form containing 85 percent to 90 percent OPCs. Prunes and prune juice have many health benefits. Grape seed extract may be more beneficial for those who are obese. One study of 211 found that Pycnogenol may help prevent edema and ankle swelling from long flights [27]. Information is shared for educational purposes only. (10), A 15-year Dutch study was published stating that 27,939 healthy female health professionals were given aspirin or a placebo for a period of time. A study of 66 healthy adults found that Pycnogenol may reduce the number of leg cramps experienced [11]. It has been studied for its effects on everything from mental function to treating high blood pressure. When pycnogenol cream was added to oral supplements in a small study of 18 people with vein ulcers, it helped ulcers heal more quickly [26]. Buying Effective Supplements for ED - Verywell Health Research indicates that Pycnogenol provides an increase in endurance performance of trained athletes. We believe that the most accurate information is found directly in the scientific source. (1, 2). In 1534, a French ship led by the famous explorer Jacques Cartier became stranded in ice near Quebec, Canada. DOI: Debra Rose Wilson, Ph.D., MSN, R.N., IBCLC, AHN-BC, CHT, 50 to 450 milligrams of pine bark extract daily, Supplements During Pregnancy: Whats Safe and Whats Not, The ADHD Diet: What Works and What Does Not, Berberine A Powerful Supplement With Many Benefits, The Top Health Benefits of Prunes and Prune Juice, What to Know About Andrographis Supplements: Potential Benefits and Uses, Kerry Boyle D.Ac., M.S., L.Ac., Dipl. ( 1) 2. What Are These Tiny Red Spots on My Skin (Petechiae)?